Organophosphorous pesticide exposure increases the frequency of sperm sex null aneuploidy.
نویسندگان
چکیده
منابع مشابه
Impact of DNA Damage on the Frequency of Sperm Chromosomal Aneuploidy in Normal and Subfertile Men
Background: Various frequencies of sperm aneuploidy are reported in sperms of subfertile patients compared to normal individuals. Moreover, sperm DNA damage is shown to be associated with male infertility. In this study, the rate of DNA damage and frequencies of aneuploidy in sperms of subfertile patients was investigated. Methods: Semen samples were obtained from healthy normal and subfertile ...
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The chemical compound temephos (0,0,0',0'-tetrametyl-0,0'-thiodi-p-phenylene phosphorothioate) is an organophosphorous pesticide that has been used in Brazil since 1967 in control campaigns against the mosquito Aedes aegypti, the vector of dengue and yellow fever. We used single cell gel electrophoresis (SCGE), SOS/umu and Ames/Salmonella assays to test the toxicity and mutagenicity of temephos...
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Organophosphorus pesticide poisoning causes tens of thousands of deaths each year across the world. Poisoning includes acute cholinergic crisis as a result of AChE inhibition, intermediate syndrome (IMS) due to neuromuscular necrosis and organophosphate-induced delayed neuropathy (OPIDN) due to inhibition of neuropathy target esterase (NTE). Standard treatment for acute poisoning involves admin...
متن کاملimpact of dna damage on the frequency of sperm chromosomal aneuploidy in normal and subfertile men
background: various frequencies of sperm aneuploidy are reported in sperms of subfertile patients compared to normal individuals. moreover, sperm dna damage is shown to be associated with male infertility. in this study, the rate of dna damage and frequencies of aneuploidy in sperms of subfertile patients was investigated. methods: semen samples were obtained from healthy normal and subfertile ...
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Chlorpyrifos is a broad spectrum moderately toxic organophosphorous insecticide. It is widely used in agriculture for pest control and in households as a termicide. However, exposure to chlorpyrifos and its metabolites can affect the public health resulting from its long residual periods in soil and water. Thus, there is an essential need to develop sensitive method for the detection of chlorpy...
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ژورنال
عنوان ژورنال: Environmental Health Perspectives
سال: 2001
ISSN: 0091-6765,1552-9924
DOI: 10.1289/ehp.011091237